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| The neural network described above does not end with the only correlation between trigeminal somatosensory centres and other motor areas but also strays into the amigdaloidei processes through a correlation with the trigeminal brainstem area. The amygdala becomes active from fear, playing an important role in the emotional response to life-threatening situations. When lab rats feel threatened, they respond by biting ferociously. The force of the bite is regulated by the motor nuclei of the trigeminal system and trigeminal brainstem Me5. The Me5 transmits proprioceptive signals from the Masticatory muscles and parodontal ligaments to trigeminal nuclei and motors. Central Amygdaloid Nucleus (ACe) projections send connections to the trigeminal motor nucleus and reticular premotor formation and directly to the Me5. | | The neural network described above does not end with the only correlation between trigeminal somatosensory centres and other motor areas but also strays into the amigdaloidei processes through a correlation with the trigeminal brainstem area. The amygdala becomes active from fear, playing an important role in the emotional response to life-threatening situations. When lab rats feel threatened, they respond by biting ferociously. The force of the bite is regulated by the motor nuclei of the trigeminal system and trigeminal brainstem Me5. The Me5 transmits proprioceptive signals from the Masticatory muscles and parodontal ligaments to trigeminal nuclei and motors. Central Amygdaloid Nucleus (ACe) projections send connections to the trigeminal motor nucleus and reticular premotor formation and directly to the Me5. |
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− | To confirm this, in a study conducted among mice, the neurons in the Central Amigdaloide nucleus (ACe) were marked after the injection of a retrograde tracer(Fast Blue), in the caudal nucleus of the Me5, indicating that the Amigdaloians send direct projections to the Me5, and suggest that the amygdala regulates the strength of the bite by modifying the neuronal activity in the Me5 through a neural facilitation..<ref>Shirasu, M., et al., ''Direct projections from the central amygdaloid nucleus to the mesencephalic trigeminal nucleus in rats.'' Brain Res, 2011. 1400: p. 19-30.https://www.ncbi.nlm.nih.gov/pubmed/?term=Direct+projections+from+the+central+amygdaloid+nucleus+to+the+mesencephalic+trigeminal+nucleus+in+rats.+Brain+Res%2C+2011</ref> | + | To confirm this, in a study conducted among mice, the neurons in the Central Amigdaloide nucleus (ACe) were marked after the injection of a retrograde tracer(Fast Blue), in the caudal nucleus of the Me5, indicating that the Amigdaloians send direct projections to the Me5, and suggest that the amygdala regulates the strength of the bite by modifying the neuronal activity in the Me5 through a neural facilitation..<ref>{{Cite book |
| + | | autore = Shirasu M |
| + | | autore2 = Takahashi T |
| + | | autore3 = Yamamoto T |
| + | | autore4 = Itoh K |
| + | | autore5 = Sato S |
| + | | autore6 = Nakamura H |
| + | | titolo = Direct projections from the central amygdaloid nucleus to the mesencephalic trigeminal nucleus in rats |
| + | | url = https://pubmed.ncbi.nlm.nih.gov/21640334/ |
| + | | volume = |
| + | | opera = Brain Res |
| + | | anno = 2011 |
| + | | editore = |
| + | | città = |
| + | | ISBN = |
| + | | PMID = 21640334 |
| + | | PMCID = |
| + | | DOI = 10.1016/j.brainres.2011.05.026 |
| + | | oaf = <!-- qualsiasi valore --> |
| + | | LCCN = |
| + | | OCLC = |
| + | }}</ref> |
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| Modifying occlusal ratios can alter oral somatosensory functions and the rehabilitative treatments of the Masticatory system should restore somatosensory functions. However, it is unclear why some patients fail to adapt to the masticatory restoration, and sensomotor disorders remain. At first, they would seem to be structural changes, not just functional ones. The primary motor cortex of the face<ref name="MFCF" /> is involved in the generation and control of facial gold movements and sensory inputs or altered motor functions, which can lead to neuroplastic changes in the M1 cortical area. <ref>{{Cite book | | Modifying occlusal ratios can alter oral somatosensory functions and the rehabilitative treatments of the Masticatory system should restore somatosensory functions. However, it is unclear why some patients fail to adapt to the masticatory restoration, and sensomotor disorders remain. At first, they would seem to be structural changes, not just functional ones. The primary motor cortex of the face<ref name="MFCF" /> is involved in the generation and control of facial gold movements and sensory inputs or altered motor functions, which can lead to neuroplastic changes in the M1 cortical area. <ref>{{Cite book |