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  }}</ref> In this same context, the work of Irma Thesleff from Helsinki, Finland, should be highlighted. She explains in her work that there are a series of transient signalling centres in the dental epithelium that play important roles in the programme of tooth development.<ref>{{Cite book  

  }}</ref> Nesse mesmo contexto, o trabalho de Irma Thesleff de Helsinque, Finlândia, merece destaque.. She explains in her work that there are a series of transient signalling centres in the dental epithelium that play important roles in the programme of tooth development.<ref>{{Cite book  

  | autore = Thesleff I

  | autore = Thesleff I

  | titolo = Current understanding of the process of tooth formation: transfer from the laboratory to the clinic

  | titolo = Current understanding of the process of tooth formation: transfer from the laboratory to the clinic